Open Source Ventilator Project, Hacker News

Open Source, Open Architecture Ventilator Engineering Design Specifications

This open source project has been created to address predicted ventilator shortage worldwide due to the COVID – (pandemic and host open source contributions) – Distribute freely

Daily Update

Updated March , Full system integration (including Arduino-based user interface) was conducted today. The BASE system passed preliminary testing. Scroll down to view the video.

Now that we know that the integrated system works, we will test in the next 2 weeks to see if it is safe before releasing the detailed build and test instructions and bill of materials

BASE model has been ventilating test lung overnight 2 nights in a row without failure

Multiple companies throughout the US have offered free manufacturing of the OS-Vent as well as private individuals

Groups in Bangladesh and Peru are working on localization of the components (replacing what we use in the current OS-Vent design by equivalent components that are readily available locally)

Faculty and students at the College of Engineering at the University of Florida are redesigning some components

Printed circuit board (PCB) – Chinese manufacturer has OS-Vent PCB design and is ready to mass produce

Pressure sensor to be used in extension of BASE model has been identified and integrated in a proof of concept model

Specifications have been altered to meet or exceed COVID ventilator specifications from UK

Added additional disclaimers to the site

OS-Vent site translated to French, Italian, Portuguese, Turkish

Exploring preliminary steps to obtain Emergency Use Authorization (EUA) from FDA

Translations

Specification Documents (Download Engineering Specifications-V1.5.1) (Controller Module Specifications-V1.0) Inspiration Module Specifications-V1.0

(Exhalation Module Specifications-V1.0) PEEP Module Specifications-V1.0 Over-Pressure Valve Module-V1.0 Anti-Asphyxia Module V1.0

Visit GitHub to contribute and view the very latest version

Communication Info Contact our team

Discuss in our Forum

Ventilator Developers – Not-UF Affiliated Forum

Overall Design Philosophy
Open source for use worldwide and contributions from all worldwide

Adult ventilator (older adults at higher risk)

Positive pressure volume control ventilation for intubated patients who are not spontaneously breathing A bare bones, safe design is better than nothing and what “nothing” means

The supplies and materials will be locally available at hardware stores

The design (s) will be validated; validation will be documented and transparent; as an academic research lab, CSSALT can do some of the verification and validation

The design (s) will be modular allowing different modules to be mixed and matched depending on local availability

Unboxed design – all parts directly accessible

Design will be inexpensive to build (parts for base model less than $ US) and assembled quickly (less than TBD hours) with readily accessible parts

Dissemination via Internet and (GitHub) https://github.com/CSSALTlab/Open_Source_Ventilator.git)

Assumptions FDA will waive clearance for the bare bones design if there is a massive shortage

Traditional medical components and supplies used in ventilators will be in short supply

Transportation will be impaired / disrupted. Locally available non-medical supplies and equipment readily available at local hardware stores such as sprinkler valves and PVC tubing will be used
Ventilator Engineering Specifications (Range

Accuracy
(Settings)

Volume Controlled Intermittent Mechanical Ventilation. Tidal volume (TV)

– (ml) ± (ml) Increments of (ml) Respiratory rate (RR) 21 – (bpm) ± 0.5 bpm Increments of 2 I: E ratio
1: 1 or 1 : 2 (1: 3 optional)
– 2 fixed settings and 1 optional setting PEEP valve 5) – cm H (2) O; Default setting 5 cm H (2) (O) ± 1 cm H 2 (O can either be adjustable in 5 cmH (2) O increments or continuously adjustable
(Air and O) (2) (supplied at (± 5 psig) kPa (FiO) (2) 0). 25 – 1.0
± 0. 16

(Anti-asphyxia valve) Opens at -3 1 cm H (2) (O) (Over-Pressure Valve) Opens at (cm H) (2) O default , adjustable up to cm H 2
O ± 5 cm H (2) (O) (Optional)
In-built blender

0). 25 – 1.0 FiO (2)
3 fixed FiO (2) settings: 0. 22, 0.5, 1.0

Variable between (% and) % in % steps preferred
Oxygen sensor 0). 25 – 1.0 FiO (2)

3 fixed FiO (2) settings: 0. 22, 0.5, 1.0

Plateau pressure Limited to (cm H) (2) O Controlled in software Peak pressure Controlled in software (Inspiratory pause) % inspiratory time Spontaneous breathing Ventilation mode
± 0. 16 ( /- 5%)

± 0. (FiO) (2) () Live stream of ventilator

Watch the ventilator live in action on Twitch

(System Integration)

Video created by David Lizdas, BSME, March , at 5: 54 pm EST and uploaded 8: 30 pm EST

Special thanks to UF MAE and [VentilatorDevelopers]

Proof of Concept Ventilator Prototype

Video created by David Lizdas, BSME, March , 5066 at 7: 54 PM EST and uploaded : (pm EST)

Adruino-controlled Proof of Concept Prototype

Video created by Gordon Gibby, MD, March 27, 01575879 at 8: 100 pm EST and uploaded March , at 9: 23 am EST

Ventilator Electronics & User Interface Prototype

Video created by Ashhar Farhan March , , uploaded March 35,

Modules

Pneumatics

Inspiratory valve – Engineering Specifications V1.0

Exhalation valve – Engineering Specifications V1.0 PEEP valve – (Engineering Specifications V1.0) Pressure Regulation (optional) – (Engineering Specifications V1.0)

Controller Module – Engineering Specifications V1.0

3D print

Body
Accessories

Electronics

Printed circuit board

Microcontroller

Software or Timing Circuit

Power Supply v DC preferred

User Interface

Contributions

Arduino Controller concept. Video here . Find code on our <a href="https://simulation.health.ufl.edu/wordpress/files/2020/03/OS-Vent_Inspiration_Module.docx"> GitHub here . <li> </li> <li> (DISCLAIMER) <p> The Open Source Ventilator information provided here (exclusive of any open source content included in it, the “Ventilator Information”) by the University of Florida Center for Safety, Simulation, and Advanced Learning Technologies (CSSALT) is provided as research information only and has not been tested for commercial use. The Ventilator Information is provided by CSSALT with permission for the recipient to freely use, copy and modify without restriction, subject to an obligation on the recipient to recognize CSSALT as the source. The design is bare bones and the necessary supplies and materials should be locally available at hardware stores or through online retailers. This design is for an <strong> adult ventilator </strong> because older adults are at a higher risk for serious medical risk of the Coronavirus. The Ventilator Information is experimental in nature and the safety or efficacy for use in humans has not been proven. </p> <p> The design, and ventilators built in accordance with the design, have not been approved by the FDA. The March FDA Enforcement Policy for Ventilators and Accessories and Other Respiratory Devices During the Coronavirus Disease COVID – 24) , (“Emergency Guidance”), however, encourages manufacturers who have not previously been engaged in medical device manufacturing, but have capability to increase supply of ventilator devices, to work collaboratively with the FDA through its Emergency Use Authorization Process (EUA). CSSALT is currently in collaboration with the FDA to establish a EUA for this design and for ventilators built from the design. </p> <p> Prior to attempting to deploy ventilators from the CCALT design, collaboration with the FDA to obtain a EUA is crucial. The FDA established the following email contact for those wishing to build ventilators under an EUA: (CDRH-COVID) – Ventilators@fda.hhs.gov . Accordingly, if you desire to build ventilators replicating the Open Source Ventilator Project design, CCSALT strongly encourages you to contact the FDA at their designated email address to collaborate with the FDA early in your deliberation process. </p> <p> <strong> DISCLAIMER: THE VENTILATOR INFORMATION IS PROVIDED “AS-IS, WHERE-IS,” WITHOUT REPRESENTATIONS, CONDITIONS, OR WARRANTIES OF ANY KIND , WHETHER EXPRESS OR IMPLIED, INCLUDING, BUT NOT LIMITED TO, WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, </strong> <strong> OR THAT THE USE OF THE </strong> <strong> VENTILATOR INFORMATION </p> <p> <strong> WILL NOT INFRINGE ANY PATENT, COPYRIGHT,  TRADEMARK, OR OTHER PROPRIETARY RIGHTS. </strong> <strong> THE RECIPIENT IS SOLELY RESPONSIBLE FOR DETERMINING THE APPROPRIATENESS OF USING, REPLICATING, OR REDISTRIBUTING THE CSSALT OPEN SOURCE VENTILATOR PROJECT INFORMATION AND DESIGN . IN THIS REGARD </strong>, <strong> THE RECIPIENT ASSUMES ALL LIABILITY FOR DAMAGES, OF WHATEVER NATURE AND DESCRIPTION, WHETHER IN CONTRACT OR IN TORT, WHICH MAY ARISE FROM THE USE OF THE VENTILATOR INFORMATION AND DESIGN. NEITHER CSSALT NOR THE UNIVERSITY OF FLORIDA, INCLUDING ITS EMPLOYEES AND AGENTS, WILL BE LIABLE TO THE RECIPIENT OR TO ANY THIRD PARTY FOR ANY LOSS, CLAIM, OR DEMAND MADE BY THE RECIPIENT, OR ANY LOSS, CLAIM, DEMAND AG RECIPIENT BY ANY OTHER PARTY, DUE TO OR ARISING FROM THE USE OF THE VENTILATOR INFORMATION AND DESIGN BY THE RECIPIENT. </strong> </p> <p></strong> </p> <p> This project is a free Hardware Project. </p> <p> Open Hardware License and Liability </li> <li> Documentation published describing hardware is licensed under the CERN-OHL -S v2. You may redistribute and modify this documentation under the terms of the CERN-OHL-S v2. ( (https://ohwr.org/project/cernohl/wikis/uploads/) (d0b7d) (e6b) bddb /cern_ohl_s_v2.txt<a href="https://simulation.health.ufl.edu/wordpress/files/2020/03/OS-Vent_Controller_Module.docx"> except otherwise stated </a></li> <li> Free Software </li> <li> Programs described / provided / linked in / to this project are free software except otherwise stated. You can redistribute it and / or modify it under the terms of the GNU General Public License as published by the Free Software Foundation, version 3 of the License, or (at your option) any later version. This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details: (http://www.gnu.org/licenses/) . </li> <li> Pictures </li> <li> Pictures are published under Creative Commons Share Alike except otherwise stated . </li> <li> </li> <li> </li> <li> Do’s and Don’ts Everything published about building the CSSALT Open Source Ventilator here is experimental at this stage. This information is intended for researchers at research institutions. It is not targeted at customers. At this time the aim of the information is to find other opinions of how to plan the CSSALT Open Source Ventilator, not to give advice on how to build one. Building an open source ventilator is potentially dangerous. Under no circumstances should anyone actually try to build an open source ventilator based on the information provided on this page without prior consultation of the contact points given in these documents. Under no circumstances should any information on this page be used or tried on human beings without prior written consent of the contact points given in these documents. We are not a law firm and we don’t provide legal services. </li> <li> </li> <li> </li> <li> </li> <li> <strong> OS-Vent @ ufl.edu         <a href="https://ohwr.org/project/cernohl/wikis/uploads/002d0b7d5066e6b3829168730237bddb/cern_ohl_s_v2.txt"> </a></strong></li> <div class="adace-slot-wrapper adace-before-last-paragraph adace-slot-wrapper-main" > <div class="adace-disclaimer"> </div> <div class="adace-slot"> <div class="adace-loader adace-loader-6629ff2203e5b"> <script> (function ($) { var $self = $('.adace-loader-6629ff2203e5b'); var $wrapper = $self.closest('.adace-slot-wrapper'); "use strict"; var adace_load_6629ff2203e5b = function(){ var viewport = $(window).width(); var tabletStart = 601; var landscapeStart = 801; var tabletEnd = 961; var content = '%3Cdiv%20class%3D%22adace_adsense_6629ff2203dd8%22%3E%3Cscript%20async%20src%3D%22%2F%2Fpagead2.googlesyndication.com%2Fpagead%2Fjs%2Fadsbygoogle.js%22%3E%3C%2Fscript%3E%0A%09%09%3Cins%20class%3D%22adsbygoogle%22%0A%09%09style%3D%22display%3Ablock%3B%22%0A%09%09data-ad-client%3D%22ca-pub-9992104173109424%22%0A%09%09data-ad-slot%3D%229859470071%22%0A%09%09data-ad-format%3D%22auto%22%0A%09%09%3E%3C%2Fins%3E%0A%09%09%3Cscript%3E%28adsbygoogle%20%3D%20window.adsbygoogle%20%7C%7C%20%5B%5D%29.push%28%7B%7D%29%3B%3C%2Fscript%3E%3C%2Fdiv%3E'; var unpack = true; if(viewport<tabletStart){ if ($wrapper.hasClass('.adace-hide-on-mobile')){ $wrapper.remove(); } } if(viewport>=tabletStart && viewport<landscapeStart){ if ($wrapper.hasClass('.adace-hide-on-portrait')){ $wrapper.remove(); } } if(viewport>=landscapeStart && viewport<tabletEnd){ if ($wrapper.hasClass('.adace-hide-on-landscape')){ $wrapper.remove(); } } if(viewport>=tabletStart && viewport<tabletEnd){ if ($wrapper.hasClass('.adace-hide-on-tablet')){ $wrapper.remove(); } } if(viewport>=tabletEnd){ if ($wrapper.hasClass('.adace-hide-on-desktop')){ $wrapper.remove(); } } if(unpack) { $self.replaceWith(decodeURIComponent(content)); } } if($wrapper.css('visibility') === 'visible' ) { adace_load_6629ff2203e5b(); } else { //fire when visible. var refreshIntervalId = setInterval(function(){ if($wrapper.css('visibility') === 'visible' ) { adace_load_6629ff2203e5b(); clearInterval(refreshIntervalId); } }, 999); } })(jQuery); </script> </div> </div> </div> <p></a> (Read More)