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Warning! Common antibiotics have been found to cause serious heart problems – Times of India, The Times of India

Warning! Common antibiotics have been found to cause serious heart problems – Times of India, The Times of India


TIMESOFINDIA.COM | Last updated on – Sep 17, 2019, 15: 00 IST

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01/ 7Common antibiotics have been found to cause serious heart problems

Till about a few years ago, people were being prescribed antibiotics for almost every health issue, regardless of how mild they were. In fact, many a times people were self prescribing antibiotics too. But that has led to a dangerous situation and exploitation of antibiotics.

There were certain germs who responded well to antibiotics but the overuse is making them increasingly resistant. This has given rise to serious infections, such as skin infections, pneumonia, ear infections, sinus infections, and meningitis and even tuberculosis.

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02/ 7(The study)

Now a new study claims that users of Fluoroquinolone face 2.4 times greater risk of developing cardiac ailments. It is only shocking to know that one of the most commonly prescribed classes of antibiotics may be associated with two types of heart problems.

The study, published in the Journal of the American College of Cardiology, found that current users of fluoroquinolone antibiotics, such as Ciprofloxacin, face a 2.4 times greater risk of developing aortic and mitral regurgitation, where the blood backflows into the heart, compared to patients who take amoxicillin, a different type of antibiotic. The greatest risk is within 30 days of use, according to the researchers at the University of British Columbia (UBC) in Canada, states PTI.

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03/ 7Antibiotics and heart problems

Recent studies have also linked the same class of antibiotics to other heart problems, they said. Some physicians favor fluoroquinolones over other antibiotics for their broad spectrum of antibacterial activity and high oral absorption, which is as effective as intravenous, or IV, treatment.

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04/ 7What experts say

“You can send patients home with a once-a-day pill,” said Mahyar Etminan, an associate professor at UBC. “This class of antibiotics is very convenient, but for the majority of cases, especially community related infections, they’re not really needed. The inappropriate prescribing may cause both antibiotic resistance as well as serious heart problems, ”said Etminan.

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05/ 7The need of the hour

The researchers hope their study helps inform the public and physicians that if patients present with cardiac issues, where no other cause has been discovered, fluoroquinolone antibiotics could possibly be a cause. “This study highlights the need to be thoughtful when prescribing antibiotics, which can sometimes cause harm,” said Bruce Carleton, a research investigator at UB C Children’s Hospital.

Scientists analyzed data from the US Food and Drug Administration’s adverse reporting system. They also analyzed a massive private insurance health claims database in the US that captures demographics, drug identification, dose prescribed and treatment duration.

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06/ 7The dangers of fluroquinolone

Researchers identified 12, 505 cases of valvular regurgitation with 125, 020 casecontrol subjects in a random sample of more than n ine million patients. They defined current fluoroquinolone exposure as an active prescription or 30 days prior to the adverse event, recent exposure as within days (to) , and past exposure as within 61 to (days prior to an incident.)

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07/ 7The risk

Scientists also compared fluoroquinolone use with amoxicillin and azithromycin. The results showed that the risk of aortic and mitral regurgitation, blood backflow into the heart, is highest with current use, followed by recent use, researchers said.

With inputs from PTI

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